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The importance of context in regulation of gene expression is now an accepted principle; yet the mechanism by which the microenvironment communicates with the nucleus and chromatin in healthy tissues is poorly understood. A functional role for nuclear and cytoskeletal architecture is suggested by the phenotypic differences observed between epithelial and mesenchymal cells…
Volume representations and manual segmentations of the volume electron microscopy datasets were performed using Amira software.
For Research Use Only. Not for use in diagnostic procedures.